Dr Amanda Edgley
Research Fellow
| telephone | +61 3 9288 3275 |
| facsmilie | +61 3 9288 2581 |
| aedgley @ medstv.unimelb.edu.au |
Profile
Dr Amanda Edgley is a Research Fellow whose research interests lie in the areas of Cardiac Disease, Hypertension, Lipid Metabolism, Diabetes and related areas.
University of Melbourne find an expert profile
Professional Activities:
Member of St Vincents Hospital Animal Ethics Committee. Journal review: Clinical and Experimental Pharmacology and Physiology, Pharmacological Research, Diabetologia, and Nephrology . Teaching Lecturing, 3rd year Science and Biomedical Science Students at Monash University. Full member of the High Blood Pressure Research Council of Australia and the International Society for Heart Research - Australasia
Qualifications
BSc (Hons) PhD
Major Grants
- Targeting Obesity - Manipulation Metabolism Using Genetically Modified Mice (NHMRC Industry Fellowship 2007)
- CCL2 DNA vaccination to prevent diabetic cardiac fibrosis (Diabetes Australia Research Trust 2007)
Selected Publications
- Stevenson K.M., Edgley A.J., Bergstrom G., Worthy K., Kett M.M. and Anderson W.P.Angiotensin II infused intrarenally causes preglomerular vascular changes and hypertension.Hypertension 2000. 36: 839-844. Impact factor 5.63, 13 citations
- Raftos J.E., Edgley A., Bookchin R.M., Etzion Z., Lew V.L., Tiffert T. Normal Ca2+ extrusion by the Ca2+ pump of intact red blood cells exposed to high glucose concentrations. Am J Physiol Cell Physiol. 2001. 280: C1449- C1454. Impact factor 3.939, 3 citations.
- Edgley AJ, Nichols NR, Anderson WP. Acute intrarenal infusion of ANG II does not stimulate immediate early gene expression in the kidney. Am J Physiol Regul Integr Comp Physiol, 282 (4): R1133-9, 2002. Impact Factor (IF) 3.802, (1 citation).
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Edgley AJ, Kett MM, Anderson WP. Evidence for renal vascular remodeling in angiotensin II-induced hypertension. J Hypertens, 21 (7): 1401-6, 2003. IF 5.218, (7 citations)
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Parkington HC, Dodd J, Luff SE, Worthy K, Coleman HA, Tare M, Anderson WP, Edgley AJ. Selective increase in renal arcuate innervation density and neurogenic constriction in chronic angiotensin II-infused rats. Hypertension, 43 (3): 643-8, 2004. IF 6.331, (3 citations).
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Shannon MF, McKenzie KU, Edgley A, Rao S, Peng K, Shweta A, Schyvens CG, Anderson WP, Wilson SR, Pittelkow YE, Ohms S, Whitworth JA. Optimizing microarray in experimental hypertension. Kidney Int, 67 (1): 364-70, 2005. IF 4.927, (1 citation).
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Edgley AJ, Thalen PG, Dahllof B, Lanne B, Ljung B, Oakes ND. PPARgamma agonist induced cardiac enlargement is associated with reduced fatty acid and increased glucose utilization in myocardium of Wistar rats. Eur J Pharmacol, 538 (1-3): 195-206, 2006. IF 2.477 (0 citations).
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Wernstedt I, Edgley A, Berndtsson A, Faldt J, Bergstrom G, Wallenius V, Jansson JO. Reduced stress- and cold-induced increase in energy expenditure in interleukin-6-deficient mice. Am J Physiol Regul Integr Comp Physiol, 291 (3): R551-7, 2006. IF 3.802, (3 citations).
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Oakes ND, Thalen P, Aasum E, Edgley A, Larsen T, Furler SM, Ljung B, Severson D. Cardiac metabolism in mice: tracer method developments and in vivo application revealing profound metabolic inflexibility in diabetes. Am J Physiol Endocrinol Metab, 290 (5): E870-81, 2006. IF 4.456, (0 citations)
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Anderson WP, Shweta A, Evans RG, Edgley AJ, Gao Y. Total peripheral resistance responsiveness during the development of secondary renal hypertension in dogs. J Hypertens, 25 (3): 649-62, 2007. IF 5.218 (0 citations)
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Edgley AJ, Evans RG, Tare M, Skordilis C, Parkington HC.In vivo regulation of endothelium-dependent vasodilation in the rat renal circulation and the effect of diabetes.Accepted Am J Physiol Regu Physiol June 2008